Hoss Nakano

So I am researching a possible head swap. F22b1 block and a pr4-4 head to go into a 99 civic 2 door with a 5 speed tranny. So I'm curious if in fact all the main parts , block , head and 5 sped manual trans will work together with the ecu that supports vtec and 5 speed man trans (original) the original motor blew and this is a alternate . the f22b1 is complete. The pr4-4 is a head I just got . the f22 has automatic trans on it. The two options for manual trans are p5b from a 01 civic V tech d17A2 block or a s40 from the original 99 motor I believe. Any suggestion or concerns with this Frankenstein project that I should consider or even not do? Let me know. This is a new venture to me.