Is it hard to change spark-plugs on a 2002 Accord coupe with the 3.0 V-6?...

 

In general, no. Just be careful not to overtorque the new ones when reinstalling, since you're essentially screwing steel into aluminum (i.e. the spark plug will win). Also, check the gap of the new plugs before you put them in. I put a little 'boot grease' on the lip of the boot, to make subsequent removal of the plug easier.

 

Thanks for the reply.
So the 3 in the back aren't too hard to get to?...

 

If the mileage is high enough it needs new plugs, I would suggest removing the upper plenum off the intake and making sure the EGR port is cleaned out.
Upper plenum to lower plenum gaskets are reusable steel, so no need to worry about having to buy gaskets. I'd also suggest having the engine not cold nor hot. ~hour after shutdown, it will make pulling the plugs easier.