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Yes it will bolt up & run but why are you looking at this particular head swap? According to flow test that have been done the F22B2 head doesn't flow as well as the F22A heads.
Sticking with the F22A head and buying a stock F22A4 exhaust manifold would be easier and cheaper than swapping the B2 head onto the F22A block. If all you need is an F22A exhaust manifold go for the exhaust manifold swap vs the head swap.
There is a port at the front of the head that needs to be tapped and plugged with a 1/8NPT plug. It's directly in the center of the head, at the very front between #2 and #3 exhaust ports. Normally this would be sealed by the headgasket but the F22Ax blocks are missing a small piece of casting that is supposed to mate up with the head so it doesn't seal. You will have to remove the head again the plug the hole.
There is a port at the front of the head that needs to be tapped and plugged with a 1/8NPT plug. It's directly in the center of the head, at the very front between #2 and #3 exhaust ports. Normally this would be sealed by the headgasket but the F22Ax blocks are missing a small piece of casting that is supposed to mate up with the head so it doesn't seal. You will have to remove the head again the plug the hole.
Thank you so much for the answer.
I was already thinking about buying a "new" F22A head, to install on my engine.
It saved me time and money.
Actually all you need to do is put the Non VTEC oil control orifice back in the block. That port is the oil feed to the head for VTEC heads. It is the hole that you have circled in green on the block. All F22 engine blocks have this oil port in the blocks, only the Non VTEC use the orifice plug. There should be no need to drill and tap anything. The plug was originally in the F22A block, you just need to find out where it went. It is a small brass plug with an o-ring seal.
or I guess you could tap the head and rely on the head gasket to seal the oil that is coming up from the block.
Orifice Assembly, Oil Control - Honda Part# 15140-PH3-000
He had a water leak, not oil. There is a casting hole in the head that leads into the water passages on the F22Bx heads that is the issue here. The F22Ax blocks are missing a small piece of casting that won't allow the headgasket to seal it shut. If you look at his photos you can see it. The very center rib of the block, between #2 and #3, doesn't extend outward far enough where it meets the head to seal the hole on the F22Bx head. I found out this issue the hard way many years ago when I put an F22B1 head on an F22A block. It will leak water all down the front of the block as soon as you fill it up because there's nothing sealing that hole.