I've checked all wiring, connections, etc... Even went as far as replace the battery numerous times (went through 2 Optima Yellow Tops and I'm pretty sure my new Oddessey is toast) and I'm still getting some sort of drain on the main battery.

I have no clue as to why this is happening but the battery will be completely dead (less than 6V) if I dont drive the car once every couple days.

I've noticed that water 'could' be blamed, but I don't understand how.

Any thoughts?

 

I'm assuming you checked the altnator ya? replaced it?