Have a 2007 accord v6 sedan
Came home from store and turned off car
Tried turning it back on and nothing....
No power. No interior lights, no horn, no nothing
I turn the key and silence. Nothing

Battery was purchased in December from Advanced Auto parts. Not sure if it’s the battery or not.

I’ve also read that it could be be a blown 100a main fuse. Is there a way to test the fuse with a multimeter?

I’m open to changing the fuse, but I’m correct in saying that the fuse will likely blow again until the underlying issue is resolved?

If the fuse is blown, would the car start if I get a battery jump?

 

check all connections to the battery. got a multimeter? check the battery voltage. I've had AAP batteries fail but not as drastically as yours.
visually check all fuses and fusible links under the hood. check and clean the ground wire and its connection to the car body

start with basic easy stuff.