I had the infamous VSS/CEL-17 problem, and replaced the VSS with an ebay part. After that I went and pulled-out the 7.5A back-up(radio) fuse located in the engine compartment. I waited for a minute, then plugged the fuse back in. The CEL came off when I started the car, and I proceeded to drive. The speedometer then went wildly dancing around and soon enough my CEL came back on. I then decided to unplug the battery for a minute and see if that'd quell the problem. Connected the battery back in, got in the car, started it up, drove around, and this time the speedo behaved normally.

My question, Is there a difference when "resetting" the car and doing the 7.5A fuse method vs, unplugging the battery? What exactly get reset when I pull the 7.5A fuse?

 

Generally, there is no real difference between disconnecting the negative battery cable or the ECU back-up fuse, other than ease of no tools needed to pull a fuse and re-inserting it.

For the 5th generation Accord, in the underhood fuse/relay box, the 7.5A fuse for the ECU is also for the Clock, TCU and radio.