I just picked up a 01 accord sedan today for a pretty decent price.
It has no automatic door lock or automatic window, so i was just wondering if i can change those to all automatic, and how hard would it be??

 

That a DX?

I don't think you can without replacing the guts of the door and even then you might end up having to replace the doors.

Personally, I'd prefer manual locks / windows, two less things that can break and in my '99 LX the only two things I've had trouble with have been... the locks and windows.

 

Heat is correct. Although the provisions are there for mounting the required 'guts' for both Power Windows and locks, the vehicle itself has harness differences and components required to control them are just not there. Even if you were to take two complete doors from a properly equipped car and swapped them in, you would still have to wire them up. It would most likely require a sub-harness which is either included or omitted when the car is built.
One avenue (seldom traveled) is aftermarket systems which can be installed.

A GOOGLE!! search should scare up several sourses.

P