Pudnite

So in about April of 2017 my 97 Civic ex started like chugging when I was going highway speeds when my car was being driven longer than an hour I'd say, then in September or October, it started to chug whenever I drove it unless I gave it full gas... Anyway, It was diagnosed with a cylinder 3 I believe misfire. Switched the coil packs and it didn't help. Changed the spark plugs and it ran like a charm again. Since then I have been delivering pizzas and just went on a 9-hour road trip and on the way back it started to do it again and it has a cylinder 4 misfire now. I just changed the spark plus about 2 or 3 months ago, could it be them again??

mk378

Coil packs? It doesn't have coil packs. It has a distributor (with one coil inside), cap and rotor, and spark plug wires.

Probably should compression test the engine before buying any more parts though.

Megalodong

As mk378 suggested: do a compression test.
Also, pull the spark plugs and inspect for fouling..post pics here of plugs.
Any coolant loss in the radiator or coolant gain/overflow in the reservoir?